Label-free visual detection of nucleic acids in biological samples with single-base mismatch detection capability.
نویسندگان
چکیده
We have combined an allosteric molecular beacon for target recognition and guanine-rich DNAzyme for signal amplification to develop a new platform for visual detection of nucleic acids with single-base mismatch detection capability. The fully DNA-structured platform can undergo color change in response to target DNA/RNA, which enables sensitive and selective visual detection in biological samples.
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ورودعنوان ژورنال:
- Chemical communications
دوره 48 4 شماره
صفحات -
تاریخ انتشار 2012